Guaranteed adherence.
Better outcomes.™

Through miniaturized, long-term biopharmaceutical implants, we seek to free patients from medication adherence challenges, minimizing the burden and maximizing the benefit of clinical treatments.

Addressing the biggest challenges in chronic disease treatment – medication non-adherence and tolerability.

An alarming percentage of patients suffering from chronic illnesses don’t take their medications as prescribed, often due to the inconveniences associated with drug administration and/or tolerability, which may be associated with fluctuating drug levels.

Watch our CEO, Dr. Adam Mendelsohn, introduce our revolutionary approach to improve chronic disease treatment with miniature, ultra long-acting drug implants.
69%

Of patients do not adhere to their medication due to forgetfulness and inertia.

Our long-term solution for life-long conditions.

At Vivani we are developing our novel NanoPortal™ implant technology for delivering the intended dose of medication steadily over extended periods of time. It has been engineered with the goal of avoiding challenges that may be associated with fluctuating drug delivery.

Our Lead Drug Candidate: NPM-139

GLP-1 for Chronic Weight Management

NPM-139 is a miniature, subdermal, semaglutide drug implant with once or twice-yearly dosing under development for chronic weight management in patients who are obese or overweight. This implant can be conveniently inserted under the skin during a quick outpatient procedure and is designed to provide steady doses of medication. Based on positive preclinical weight loss data, NPM-139 is now planned for clinical development. NPM-115, a miniature, six-month, subdermal, subdermal, exenatide implant, was the first NanoPortal implant to achieve 6-month feasibility in animals and was used in LIBERATE-1, the Phase 1, first-in-human application of the company’s proprietary NanoPortal implant technology. LIBERATE-1 achieved all primary objectives and has paved the way for future development of the technology with our emerging pipeline.

Also Developing Candidate: NPM-133

GLP-1 for Type 2 Diabetes

NPM-133 is a miniature, six-month, subdermal, semaglutide drug implant under development to treat patients with type 2 diabetes. This device can also be conveniently inserted under the skin during a quick outpatient procedure and is designed to provide steady doses of medication for up to six months.

News & Updates

09.17.25
Vivani Medical Announces Record Date for Spin-off of Cortigent Neuromodulation Subsidiary to…

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09.04.25
Vivani Medical Provides Update on Clinical Development Plans for NPM-139 Semaglutide Implant…

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08.20.25
Vivani Medical CEO Adam Mendelsohn to Present at the H.C. Wainwright 27th…

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08.13.25
Vivani Medical Provides Business Update Including $10M Equity Financing and Reports Second…

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06.11.25
Vivani Medical Appoints Anthony Baldor as Chief Financial Officer

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06.10.25
Vivani Medical to Present at the 2025 BIO International Convention

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05.29.25
Vivani Medical Announces Filing of Form 10 Registration Statement for Planned Spin-Off…

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05.13.25
Vivani Medical Provides Business Update Including $3M Equity Financing and Reports First…

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05.07.25
Vivani Medical to Present at the American Association of Pharmaceutical Scientists’ “Beyond…

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04.16.25
Vivani Medical to Participate in Virtual Fireside Chat Hosted by H.C. Wainwright…

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Current Disease Targets of NanoPortal Platform Technology

Obesity / Chronic
Weight Management

Type 2 Diabetes

Canine and Feline
Cardiometabolic Disorders