Through miniaturized, long-term biopharmaceutical implants, we seek to free patients from medication adherence challenges, minimizing the burden and maximizing the benefit of clinical treatments.
An alarming percentage of patients suffering from chronic illnesses don’t take their medications as prescribed, often due to the inconveniences associated with drug administration and/or tolerability, which may be associated with fluctuating drug levels.
Watch our CEO, Dr. Adam Mendelsohn, introduce our revolutionary approach to improve chronic disease treatment with miniature, ultra long-acting drug implants.NPM-139 is a miniature, subdermal, semaglutide drug implant with once or twice-yearly dosing under development for chronic weight management in patients who are obese or overweight. This implant can be conveniently inserted under the skin during a quick outpatient procedure and is designed to provide steady doses of medication. Based on positive preclinical weight loss data, NPM-139 is now planned for clinical development. NPM-115, a miniature, six-month, subdermal, subdermal, exenatide implant, was the first NanoPortal implant to achieve 6-month feasibility in animals and was used in LIBERATE-1, the Phase 1, first-in-human application of the company’s proprietary NanoPortal implant technology. LIBERATE-1 achieved all primary objectives and has paved the way for future development of the technology with our emerging pipeline.
NPM-133 is a miniature, six-month, subdermal, semaglutide drug implant under development to treat patients with type 2 diabetes. This device can also be conveniently inserted under the skin during a quick outpatient procedure and is designed to provide steady doses of medication for up to six months.